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Native DGC structure rationalizes muscular dystrophy-causing mutations

Hoffman, E. P., Brown, R. H. Jr. & Kunkel, L. M. Dystrophin: the protein product of the Duchenne muscular dystrophy

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Neutralizing GDF-15 can overcome anti-PD-1 and anti-PD-L1 resistance in solid tumours

Patients and treatment The trial was termed GDFATHER, for GDF-15 antibody-mediated human effector cell relocation (ClinicalTrials.gov NCT04725474). This study was

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Imaging a new class of magnetism

RESEARCH BRIEFINGS 11 December 2024 Using X-ray microscopy, the properties of a new class of magnetism — altermagnetism — have

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Constraint reveals the mitochondrial genome sites most important for health and disease

RESEARCH BRIEFINGS 11 December 2024 Mitochondrial DNA (mtDNA) is the part of the genome found in mitochondria, the ‘powerhouses’ of

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Will artificial intelligence help or hinder progress on the SDGs?

Serge Stinckwich is working to understand how to use AI tools sustainably.Credit: UNDESA/DPIDG/UNPOG There is a lot of interest from

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A lipid made by tumour cells reprograms immune cells

Nature, Published online: 11 December 2024; doi:10.1038/d41586-024-03855-8 Cancer cells often become unresponsive to multiple types of therapy. It emerges that

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Nanoscale imaging and control of altermagnetism in MnTe

Our vector mapping includes the local real-space detection of the orientation of the altermagnetic order vector, L = M1 − M2, with respect to

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What’s next for Syria’s science? A view from Nature’s reporter who was a refugee

Hello Nature readers, would you like to get this Briefing in your inbox free every day? Sign up here. Magnetic

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Meet the Latina scientists advancing health and policy

Life as a scientist in Latin America isn’t always easy — and this is especially true for women. Latina researchers

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Climate and health needs are driving materials advances

DNA purification microchip.Credit: Dennis Kunkel Microscopy/SPL Much of the scientific discourse around climate change, at least in public-policy debates, relates