Nucleosome fibre topology guides transcription factor binding to enhancers
Inclusion and ethics All animal experiments for the iPS cell and iTS cell generation from MEFs were approved by the
Record-low Antarctic sea ice in 2023 increased ocean heat loss and storms
Data sources The surface flux, meteorological variables and sea-ice concentration presented in our study are from the European Centre for
Atmospheric rivers lead to heat extremes
RESEARCH BRIEFINGS 18 December 2024 Atmospheric rivers are long, narrow bands of water vapour in the lower atmosphere that often
Machine learning helps to determine the diverse conformations of RNA molecules
RESEARCH BRIEFINGS 18 December 2024 An innovative technique called HORNET uses atomic force microscopy and a machine-learning architecture called a
Four-component protein nanocages designed by programmed symmetry breaking
We generated base T = 1 tetrahedral, octahedral and icosahedral cages from the BGL17_A32 homotrimer using RPXdock20,21 to sample rotational and translational
Sea ice is shrinking during Antarctic winter: here’s what it means for Earth’s oceans and atmosphere
Nature, Published online: 18 December 2024; doi:10.1038/d41586-024-04078-7 The extent of Antarctic sea ice dropped precipitously in 2023. Analysis shows that
Vapour-deposited thin films raise the possibility of portable nuclear clocks
RESEARCH BRIEFINGS 18 December 2024 A rare isotope, thorium-229, exhibits a unique low-energy nuclear transition that could form the basis
Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing
Data reporting The chosen sample sizes were similar to those used in this field: n = 4–5 samples were used to evaluate
Lithocholic acid phenocopies anti-ageing effects of calorie restriction
Data reporting The chosen sample sizes were similar to those used in the field: n = 4–12 samples were used to evaluate
Algae use the underwater light spectrum to sense depth
Nature, Published online: 18 December 2024; doi:10.1038/d41586-024-04079-6 Aquatic algae called diatoms have been found to use light-sensing proteins as depth