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Glutamate acts on acid-sensing ion channels to worsen ischaemic brain injury

Animals Wild-type C57BL/6J mice were purchased from Vital River company (China) and housed in groups, in the animal facility at

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Phage anti-CRISPR control by an RNA- and DNA-binding helix–turn–helix protein

Aravind, L., Anantharaman, V., Balaji, S., Babu, M. M. & Iyer, L. M. The many faces of the helix–turn–helix domain:

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Brainstem Dbh+ neurons control allergen-induced airway hyperreactivity

Mice All mice were housed, and all experimental procedures were carried out in American Association for Accreditation of Laboratory, Animal

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Blowout! Satellites reveal one of the largest methane leaks on record

Nature, Published online: 11 July 2024; doi:10.1038/d41586-024-02267-y An oil well in Kazakhstan dumped more than 100,000 tonnes of the potent

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The quantum transition of the two-dimensional Ising spin glass

Model and simulations Our quantum spins occupy the nodes of a square lattice of side L, endowed with PBCs. The

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Single-cell atlas of the human brain vasculature across development, adulthood and disease

Wälchli, T. et al. Shaping the brain vasculature in development and disease in the single-cell era. Nat. Rev. Neurosci. 24,

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Alveolar fibroblast lineage orchestrates lung inflammation and fibrosis

Buechler, M. B. et al. Cross-tissue organization of the fibroblast lineage. Nature 593, 575–579 (2021). Article  CAS  PubMed  Google Scholar 

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In situ targeted base editing of bacteria in the mouse gut

Strains and media The E. coli and λ prophage genomes were engineered using a strategy derived from λ red homologous recombination coupled

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Deeper and stronger North Atlantic Gyre during the Last Glacial Maximum

Hogg, A. M. & Gayen, B. Ocean gyres driven by surface buoyancy forcing. Geophys. Res. Lett. 47, e2020GL088539 (2020). Article 

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Interferon subverts an AHR–JUN axis to promote CXCL13<sup>+</sup> T cells in lupus

Nature, Published online: 10 July 2024; doi:10.1038/s41586-024-07627-2 Insufficient AHR activation has been suggested in SLE, and augmenting AHR activation therapeutically