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Substrate binding and inhibition mechanism of norepinephrine transporter

Bönisch, H. & Brüss, M. The norepinephrine transporter in physiology and disease. Handb. Exp. Pharmacol. 175, 485–524 (2006). Article  Google

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The genomic basis of childhood T-lineage acute lymphoblastic leukaemia

Department of Pathology, St Jude Children’s Research Hospital, Memphis, TN, USA Petri Pölönen, Danika Di Giacomo, Abdelrahman Elsayed, Shunsuke Kimura, Francesca Benini, Lindsey E. Montefiori, Ilaria

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Precision spectroscopy on 9Be overcomes limitations from nuclear structure

Historically, advances in precision atomic spectroscopy have progressed alongside the development of the quantum theories of nature to successfully explain

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Origin and evolution of the bread wheat D genome

Establishing Ae. tauschii genomic resources Plant material We compiled a database comprising 1,124 Ae. tauschii accessions with associated passport data

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Unimolecular net heterolysis of symmetric and homopolar σ-bonds

According to valence bond theory, the fission of σ-bonds from their ground (S0) or lowest excited states (S1, T1) through

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Structural basis for the activity of the type VII CRISPR–Cas system

Altae-Tran, H. et al. Uncovering the functional diversity of rare CRISPR-Cas systems with deep terascale clustering. Science 382, eadi1910 (2023).

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Stonehenge’s central rock probably came from Scotland

RESEARCH BRIEFINGS 14 August 2024 The origins of the stones that make up the ancient monument Stonehenge can provide insights

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Human organoids with an autologous tissue-resident immune compartment

Human samples Human intestinal tissue samples and annotated data were obtained, and experimental procedures performed, within the framework of the

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Molecular architecture of coronavirus double-membrane vesicle pore complex

Plasmid constructs Codon-optimized SARS-CoV-2 nsp3 and nsp4 sequences from the Wuhan-Hu-1 SARS-CoV-2 genome were amplified by the donor plasmids pEGFPN1-nsp3-EGFP

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Innovative way to break chemical bonds broadens horizons for making molecules

NEWS AND VIEWS 14 August 2024 A fresh approach to breaking chemical bonds combines the energy of heat and light,