NATURE

Dopamine dynamics are dispensable for movement but promote reward responses

Liu, C., Goel, P. & Kaeser, P. S. Spatial and temporal scales of dopamine transmission. Nat. Rev. Neurosci. 22, 345–358…

2 months ago

Spatial proteomics identifies JAKi as treatment for a lethal skin disease

Patient biopsiesSkin tissue biopsies were obtained during routine histopathological diagnostic procedures. In the standard DVP proteomic cohort, patients with TEN…

2 months ago

A bacterial immunity protein directly senses two disparate phage proteins

Strains and growth conditionsAll bacterial and phage strains used in this study are listed in Supplementary Table 1. E. coli…

2 months ago

Glucose-sensitive insulin with attenuation of hypoglycaemia

Synthesis of buildings blocks, insulin conjugate NNC2215 and control compound NNC2215aDetailed synthesis of NNC2215 and the control compound NNC2215a is…

2 months ago

Circadian plasticity evolves through regulatory changes in a neuropeptide gene

Rieger, D., Stanewsky, R. & Helfrich-Forster, C. Cryptochrome, compound eyes, Hofbauer-Buchner eyelets, and ocelli play different roles in the entrainment…

2 months ago

Glucose has a surprise role in directing cell fate and migration

NEWS AND VIEWS 16 October 2024 An unexpected link has been found between the metabolic pathways that produce energy for…

2 months ago

Harnessing plasticity in sequential metamaterials for ideal shock absorption

Schaedler, T. A. et al. Ultralight metallic microlattices. Science 334, 962–965 (2011).Article  ADS  CAS  PubMed  Google Scholar  Zheng, X. et…

2 months ago

An ancient ecospecies of Helicobacter pylori

Genome collectionWe collected a total of 9,188 Helicobacter whole-genome sequences from public and private sources, including 4,210 H. pylori and one H.…

2 months ago

Young asteroid families as the primary source of meteorites

Chladni, E. F. F. Über den Ursprung der von Pallas Gefundenen und anderer ihr ähnlicher Eisenmassen, und Über Einige Damit…

2 months ago

Neuropeptide signalling orchestrates T cell differentiation

Kamperschroer, C. & Quinn, D. G. The role of proinflammatory cytokines in wasting disease during lymphocytic choriomeningitis virus infection. J.…

2 months ago