NATURE

Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis

MaterialsA list of all reagents and resources with the source and identifier is provided in Supplementary Table 3.Mouse strainsC57BL/6J, C57BL/6J…

5 months ago

Serious errors plague DNA tool that’s a workhorse of biology

Plasmids (shown here in a coloured transmission electron micrograph with various genes highlighted) are circular DNA structures used in biology…

5 months ago

Plasticity in single-crystalline Mg3Bi2 thermoelectric material

Gelbstein, Y. et al. Physical, mechanical, and structural properties of highly efficient nanostructured n- and p-silicides for practical thermoelectric applications.…

5 months ago

Alzheimer’s plaques and tangles revealed by 3D microscopy

NEWS AND VIEWS 10 July 2024 Amyloid-β peptides and tau proteins form filaments in the brain in Alzheimer’s disease. Using…

5 months ago

Dissociable hindbrain GLP1R circuits for satiety and aversion

Wadden, T. A. et al. Effect of subcutaneous semaglutide vs placebo as an adjunct to intensive behavioral therapy on body…

5 months ago

Speedy stars blow the cover of hidden black hole

Nature, Published online: 10 July 2024; doi:10.1038/d41586-024-02135-9Fast-moving stars have been discovered in the middle of the nearby star cluster ω…

5 months ago

CryoET of β-amyloid and tau within postmortem Alzheimer’s disease brain

Data reportingNo statistical methods were used to predetermine sample size. Experiments were not randomized. The investigators were not blinded to…

5 months ago

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You took 112 photos within an hour today! By my records, this is the first time you’ve cooked pasta with…

5 months ago

A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection

Animals and viral infection modelsSix-week-old C57BL6/J male mice were purchased from Janvier or Charles River. H-2KbSIINFEKL-restricted OT-1 TCR-transgenic CD45.1+ mice…

5 months ago

Emergence of large-scale cell death through ferroptotic trigger waves

ReagentsErastin (Cayman, 17754), RLS-3 (MedChemExpress, HY-100218A), ferrostatin-1 (Cayman, 17729), necrostatin-1 (Cayman, 11658), Z-VAD-FMK (Cayman, 14463), ionomycin (Sigma-Aldrich, I9657), staurosporine (MedChemExpress,…

5 months ago