NATURE

In situ analysis reveals the TRiC duty cycle and PDCD5 as an open-state cofactor

Cell cultureHEK (HEK Flp-In T-Rex 293, Invitrogen) cells were cultured in DMEM (Sigma-Aldrich) supplemented with 10% fetal bovine serum (Gibco)…

4 months ago

Strong-field quantum control in the extreme ultraviolet domain using pulse shaping

Strong-field phenomena play an important part in our understanding of the quantum world. Light–matter interactions beyond the perturbative limit can…

4 months ago

Liquid metal pumps itself out of gels to make artificial vasculature

Campbell, J. Complete Casting Handbook: Metal Casting Processes, Metallurgy, Techniques and Design (Butterworth-Heinemann, 2015). Google Scholar  Sundaram, S. et al.…

4 months ago

Structure of apolipoprotein B100 bound to the low-density lipoprotein receptor

Segrest, J. P., Jones, M. K., De Loof, H. & Dashti, N. Structure of apolipoprotein B-100 in low density lipoproteins.…

4 months ago

Large global-scale vegetation sensitivity to daily rainfall variability

Pendergrass, A. G., Knutti, R., Lehner, F., Deser, C. & Sanderson, B. M. Precipitation variability increases in a warmer climate.…

4 months ago

Lithium extraction from low-quality brines

Wulandari, T., Fawcett, D., Majumder, S. B. & Poinern, G. E. J. Lithium‐based batteries, history, current status, challenges, and future…

4 months ago

A gut fungus protects mice against parasitic worms but increases allergies

Nature, Published online: 11 December 2024; doi:10.1038/d41586-024-03651-4It has been hard to find fungi that normally reside in the mouse gut.…

4 months ago

Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia

Chappell, L. C., Cluver, C. A., Kingdom, J. & Tong, S. Pre-eclampsia. Lancet 398, 341–354 (2021).Article  CAS  PubMed  Google Scholar …

4 months ago

Native DGC structure rationalizes muscular dystrophy-causing mutations

Hoffman, E. P., Brown, R. H. Jr. & Kunkel, L. M. Dystrophin: the protein product of the Duchenne muscular dystrophy…

4 months ago

Neutralizing GDF-15 can overcome anti-PD-1 and anti-PD-L1 resistance in solid tumours

Patients and treatmentThe trial was termed GDFATHER, for GDF-15 antibody-mediated human effector cell relocation (ClinicalTrials.gov NCT04725474). This study was conducted…

4 months ago