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Structural basis for transthiolation intermediates in the ubiquitin pathway

Cloning Cloning of S. pombe Uba1, Cys-Ub with an N-terminal Ulp1-cleavable His6–Smt3 tag, and Ub without tags was described previously15,17,52.

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Substrate binding and inhibition mechanism of norepinephrine transporter

Bönisch, H. & Brüss, M. The norepinephrine transporter in physiology and disease. Handb. Exp. Pharmacol. 175, 485–524 (2006). Article  Google

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Don’t Miss Out on McDonald’s ‘New’ Collectible Cups

For lots of people, going to McDonald’s isn’t just about the affordable food. It’s also about nostalgia.  If you were

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The genomic basis of childhood T-lineage acute lymphoblastic leukaemia

Department of Pathology, St Jude Children’s Research Hospital, Memphis, TN, USA Petri Pölönen, Danika Di Giacomo, Abdelrahman Elsayed, Shunsuke Kimura, Francesca Benini, Lindsey E. Montefiori, Ilaria

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O'Neil wants 'key' Wolves transfers after losing top players

Gary O’Neil has steadied the ship at Wolverhampton Wanderers after being appointed just days before the 2023/24 season. Fast forward

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Precision spectroscopy on 9Be overcomes limitations from nuclear structure

Historically, advances in precision atomic spectroscopy have progressed alongside the development of the quantum theories of nature to successfully explain

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Origin and evolution of the bread wheat D genome

Establishing Ae. tauschii genomic resources Plant material We compiled a database comprising 1,124 Ae. tauschii accessions with associated passport data

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Unimolecular net heterolysis of symmetric and homopolar σ-bonds

According to valence bond theory, the fission of σ-bonds from their ground (S0) or lowest excited states (S1, T1) through