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Postsynaptic competition between calcineurin and PKA regulates mammalian sleep–wake cycles

Diering, G. H. et al. Homer1a drives homeostatic scaling-down of excitatory synapses during sleep. Science 355, 511–515 (2017). Article  ADS 

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Imaging shapes of atomic nuclei in high-energy nuclear collisions

Accessing information in the intrinsic frame The nuclear shape in the intrinsic frame is not directly observable in low-energy experiments.

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Intermittent rate coding and cue-specific ensembles support working memory

Subjects Three adult male rhesus monkeys (Macaca mulatta), aged 11, 12 and 8 years, participated in the experiment. Monkeys A, H

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Mysterious radio bursts mostly come from massive galaxies

Nature, Published online: 06 November 2024; doi:10.1038/d41586-024-03465-4 Powerful bursts of radio waves from distant galaxies are typically linked to young

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Cellular ATP demand creates metabolically distinct subpopulations of mitochondria

Spinelli, J. B. & Haigis, M. C. The multifaceted contributions of mitochondria to cellular metabolism. Nat. Cell Biol. 20, 745–754

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Ab initio characterization of protein molecular dynamics with AI2BMD

Protein fragmentation approach Generally speaking, proteins are composed of 20 kinds of amino acid, each of which has a common

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Surprise finding reveals mitochondrial ‘energy factories’ come in two different types

Download the Nature Podcast 6 November 2024 In this episode: 00:46 Mitochondria divide their labour to help cells thrive Researchers

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Bioelastic state recovery for haptic sensory substitution

Bolanowski, S. J. et al. Four channels mediate the mechanical aspects of touch. J. Acoust. Soc. Am. 84, 1680–1694 (1988).

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Layered hybrid superlattices as designable quantum solids

Alferov, Z. I. Nobel Lecture: The double heterostructure concept and its applications in physics, electronics, and technology. Rev. Mod. Phys.

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Automated real-world data integration improves cancer outcome prediction

Patients This study primarily analysed data for patients with tumour genomic sequencing and completed tumour registry entries from two partially