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Crosslinking intermodular condensation in non-ribosomal peptide biosynthesis

Felnagle, E. A. et al. Nonribosomal peptide synthetases involved in the production of medically relevant natural products. Mol. Pharm. 5,

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A stable zeolite with atomically ordered and interconnected mesopore channel

OSDA synthesis The OSDA used in this work is a di-quaternary phosphonium cation (bis-1,8(tricyclohexyl phosphonium) octamethylene, denoted as Tri-Cy-dC8, consisting

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Self-organized patterning of crocodile head scales by compressive folding

Animal husbandry Fertilized crocodile eggs (imported from Seronera Crocodile Farm) were transported to the University of Geneva and incubated at

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Distant sparkles hint at how the Milky Way formed

NEWS AND VIEWS 11 December 2024 The JWST has captured images of the Firefly Sparkle — a galaxy that resembles

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Small-molecule inhibition of SARS-CoV-2 NSP14 RNA cap methyltransferase

Phillips, N. The coronavirus is here to stay — here’s what that means. Nature 590, 382–384 (2021). Article  ADS  CAS 

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Continuous collective analysis of chemical reactions

Lehmann, J. W., Blair, D. J. & Burke, M. D. Towards the generalized iterative synthesis of small molecules. Nat. Rev.

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Lipid-delivery system could treat life-threatening pregnancy complication

Nature, Published online: 11 December 2024; doi:10.1038/d41586-024-03853-w Pre-eclampsia is a common and dangerous pregnancy-related illness. Using tiny lipid particles to

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Structure and assembly of the dystrophin glycoprotein complex

Campbell, K. P. & Kahl, S. D. Association of dystrophin and an integral membrane glycoprotein. Nature 338, 259–262 (1989). Article 

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In situ analysis reveals the TRiC duty cycle and PDCD5 as an open-state cofactor

Cell culture HEK (HEK Flp-In T-Rex 293, Invitrogen) cells were cultured in DMEM (Sigma-Aldrich) supplemented with 10% fetal bovine serum

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Strong-field quantum control in the extreme ultraviolet domain using pulse shaping

Strong-field phenomena play an important part in our understanding of the quantum world. Light–matter interactions beyond the perturbative limit can