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Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma

Xie, X. P. et al. Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy. Dev.

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An integrated transcriptomic cell atlas of human neural organoids

Metadata curation and harmonization of human neural organoid scRNA-seq datasets We included 33 human neural organoid data from a total

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A multi-omic atlas of human embryonic skeletal development

Sample acquisition and ethics Developing human limb and cranium tissue samples were obtained from elective terminations under REC 96/085 with

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Examining the role of common variants in rare neurodevelopmental conditions

Cohort descriptions and phenotypes DDD The aim of the DDD study is to find molecular diagnoses for families and patients

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This malaria vaccine is delivered by a mosquito bite

Some mosquitos carry the parasite Plasmodium falciparum, which transmits malaria.Credit: CDC/Science Photo Library Scientists have developed a new vaccination strategy

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A functional microbiome catalogue crowdsourced from North American rivers

Vannote, R. L., Minshall, G. W., Cummins, K. W., Sedell, J. R. & Cushing, C. E. The river continuum concept.

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Nonlinear receptive fields evoke redundant retinal coding of natural scenes

Tissue preparation and electrophysiology We recorded spiking activity from retinas of three adult male marmoset monkeys (Callithrix jacchus), 12, 13

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Direct magnetic imaging of fractional Chern insulators in twisted MoTe2

Finkler, A. et al. Self-aligned nanoscale SQUID on a tip. Nano Lett. 10, 1046–1049 (2010). Article  ADS  CAS  PubMed  Google

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Cephalopod-inspired jetting devices for gastrointestinal drug delivery

Jet physics and theoretical model To study the influence of jetting parameters (ampule pressure, jet diameter and jet velocity) on

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Single-molecule states link transcription factor binding to gene expression

Spitz, F. & Furlong, E. E. M. Transcription factors: from enhancer binding to developmental control. Nat. Rev. Genet. 13, 613–626