NATURE

Nucleosome fibre topology guides transcription factor binding to enhancers

Inclusion and ethicsAll animal experiments for the iPS cell and iTS cell generation from MEFs were approved by the University…

3 days ago

Record-low Antarctic sea ice in 2023 increased ocean heat loss and storms

Data sourcesThe surface flux, meteorological variables and sea-ice concentration presented in our study are from the European Centre for Medium-Range…

3 days ago

Atmospheric rivers lead to heat extremes

RESEARCH BRIEFINGS 18 December 2024 Atmospheric rivers are long, narrow bands of water vapour in the lower atmosphere that often…

3 days ago

Machine learning helps to determine the diverse conformations of RNA molecules

RESEARCH BRIEFINGS 18 December 2024 An innovative technique called HORNET uses atomic force microscopy and a machine-learning architecture called a…

3 days ago

Four-component protein nanocages designed by programmed symmetry breaking

We generated base T = 1 tetrahedral, octahedral and icosahedral cages from the BGL17_A32 homotrimer using RPXdock20,21 to sample rotational and translational…

3 days ago

Sea ice is shrinking during Antarctic winter: here’s what it means for Earth’s oceans and atmosphere

Nature, Published online: 18 December 2024; doi:10.1038/d41586-024-04078-7The extent of Antarctic sea ice dropped precipitously in 2023. Analysis shows that this…

3 days ago

Vapour-deposited thin films raise the possibility of portable nuclear clocks

RESEARCH BRIEFINGS 18 December 2024 A rare isotope, thorium-229, exhibits a unique low-energy nuclear transition that could form the basis…

3 days ago

Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing

Data reportingThe chosen sample sizes were similar to those used in this field: n = 4–5 samples were used to evaluate the…

3 days ago

Lithocholic acid phenocopies anti-ageing effects of calorie restriction

Data reportingThe chosen sample sizes were similar to those used in the field: n = 4–12 samples were used to evaluate the…

3 days ago

Algae use the underwater light spectrum to sense depth

Nature, Published online: 18 December 2024; doi:10.1038/d41586-024-04079-6Aquatic algae called diatoms have been found to use light-sensing proteins as depth indicators.…

3 days ago