NATURE

Structural basis of archaeal FttA-dependent transcription termination

Sanders, T. et al. FttA is a CPSF73 homologue that terminates transcription in Archaea. Nat. Microbiol. 5, 545–553 (2020).Article  CAS …

3 months ago

AARS1 and AARS2 sense l-lactate to regulate cGAS as global lysine lactyltransferases

Zhang, D. et al. Metabolic regulation of gene expression by histone lactylation. Nature 574, 575–580 (2019).Article  ADS  CAS  PubMed  PubMed…

3 months ago

Jet stream controls on European climate and agriculture since 1300 ce

Stendel, M., Francis, J., White, R., Williams, P. D. & Woollings, T. in Climate Change 3rd edn (ed. Letcher, T.…

3 months ago

Human hippocampal and entorhinal neurons encode the temporal structure of experience

ParticipantsThe participants were 17 patients with intractable epilepsy who were implanted with depth electrodes to delineate a potentially surgically treatable…

3 months ago

Larger and more instructable language models become less reliable

Figure 2 shows the results of a selection of models in the GPT and LLaMA families, increasingly scaled up, with…

3 months ago

The genetic architecture of protein stability

Combinatorial mutagenesis library designsCombinatorial library 1Library 1 was designed using a computationally efficient greedy strategy to search for the largest…

3 months ago

The evolution of private reputations in information-abundant landscapes

Roberts, G. et al. The benefits of being seen to help others: indirect reciprocity and reputation-based partner choice. Philos. Trans.…

3 months ago

Forest fire size amplifies postfire land surface warming

Datasets of forest fire, land surface characteristics, surface energy and water fluxesFire eventsInformation on individual fire events was obtained from…

3 months ago

On human-in-the-loop optimization of human–robot interaction

Demir, K. A., Döven, G. & Sezen, B. Industry 5.0 and human-robot co-working. Procedia Comput. Sci. 158, 688–695 (2019).Article  Google…

3 months ago

Future increase in extreme El Niño supported by past glacial changes

McPhaden, M. J., Zebiak, S. E. & Glantz, M. H. ENSO as an integrating concept in Earth science. Science 314,…

3 months ago