State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China
Fuchu He, Cheng Chang, Ying Jiang, Yang Li, Aihua Sun, Liujun Tang, Chanjuan Wang, Xiaowen Wang, Yan Wang, Linhai Xie, Xiao Yang, Lingqiang Zhang, Yunping Zhu, Chenxi Jia, Chaoying Li, Dong Li, Yanchang Li, Zhongyang Liu, Jian Wang, Ping Xu, Wantao Ying & Xiaobo Yu
International Academy of Phronesis Medicine (Guangdong), Guangdong, China
Fuchu He, Yuezhong He, Tianhao Xu & Yu Zi Zheng
Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland
Ruedi Aebersold
Macquarie Medical School, Macquarie University, Sydney, New South Wales, Australia
Mark S. Baker
Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University) and Key Laboratory of Tumor Immunopathology, Ministry of Education of China, Chongqing, China
Xiuwu Bian
Institute of Health Service and Transfusion Medicine, Beijing, China
Xiaochen Bo
Department of Pathology and The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA
Daniel W. Chan & Daniel W. Chan
Key Laboratory of Systems Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China
Luonan Chen
Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People’s Liberation Army, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research, Beijing, China
Xiangmei Chen
Institute of Chemistry, Academia Sinica, Taipei, China
Yu-Ju Chen
National Biomedical Imaging Center, State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking-Tsinghua Center for Life Sciences, College of Future Technology, Peking University, Beijing, China
Heping Cheng
School of Biological Sciences, Queen’s University of Belfast, Belfast, UK
Ben C. Collins
Functional Proteomics Laboratory, Centro Nacional de Biotecnología-CSIC, Madrid, Spain
Fernando Corrales
Computational Systems Biochemistry Research Group, Max-Planck Institute of Biochemistry, Martinsried, Germany
Jürgen Cox
AI for Science Institute, Beijing, China
Weinan E & Weinan E
Center for Machine Learning Research, Peking University, Beijing, China
Weinan E & Weinan E
Advanced Clinical Biosystems Research Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA
Jennifer E. Van Eyk & Jennifer E. Van Eyk
Department of Liver Surgery and Transplantation, Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China
Jia Fan & Qiang Gao
Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, Victoria, Australia
Pouya Faridi
Monash Proteomics and Metabolomics Platform, Department of Medicine, School of Clinical Sciences, Monash University, Clayton, Victoria, Australia
Pouya Faridi
School of Pharmaceutical Sciences and Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
Daniel Figeys
The D. H. Chen School of Universal Health, Zhejiang University, Hangzhou, China
George Fu Gao
Pengcheng Laboratory, Shenzhen, China
Wen Gao
School of Electronic Engineering and Computer Science, Peking University, Beijing, China
Wen Gao
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada
Zu-Hua Gao & Yu Zi Zheng
Department of Chemistry, University of Tokyo, Tokyo, Japan
Keisuke Goda
Department of Bioengineering, University of California, Los Angeles, California, USA
Keisuke Goda
Institute of Technological Sciences, Wuhan University, Wuhan, Hubei, China
Keisuke Goda
Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore
Wilson Wen Bin Goh
School of Medicine, Southern University of Science and Technology, Shenzhen, China
Dongfeng Gu
Department of Nutrition, Tianjin Institute of Environmental and Operational Medicine, Tianjin, China
Changjiang Guo & Xinxing Wang
School of Medicine, Westlake University, Hangzhou, China
Tiannan Guo & Yi Zhu
Westlake Center for Intelligent Proteomics, Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China
Tiannan Guo & Yi Zhu
Research Center for Industries of the Future, School of Life Sciences, Westlake University, Hangzhou, China
Tiannan Guo & Yi Zhu
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, the Netherlands
Albert J. R. Heck
Netherlands Proteomics Center, Utrecht, the Netherlands
Albert J. R. Heck
European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK
Henning Hermjakob & Juan Antonio Vizcaíno
Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA
Tony Hunter
Department of Head & Neck Surgery, Division of Surgery & Surgical Oncology, Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Singapore
Narayanan Gopalakrishna Iyer
OncoProteomics Laboratory, Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands
Connie R. Jimenez
Advanced Glycoscience Research Cluster, School of Biological and Chemical Sciences, University of Galway, Galway, Ireland
Lokesh Joshi
Departments of Molecular Biosciences, Departments of Chemistry, Northwestern University, Evanston, IL, USA
Neil L. Kelleher
David R. Cheriton School of Computer Science, University of Waterloo, Waterloo, Ontario, Canada
Ming Li
Central China Institute of Artificial Intelligence, Henan, China
Ming Li
Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore
Qingsong Lin
CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
Cui Hua Liu
Department of Structural Biology, Leibniz-Forschungsinstitut für MolekularePharmakologie (FMP), Berlin, Germany
Fan Liu
State Key Laboratory of Membrane Biology, Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
Guang-Hui Liu
Cancer Biology Institute, Yale University School of Medicine, West Haven, CT, USA
Yansheng Liu
State Key Laboratory of Molecular Oncology, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Zhihua Liu
UKM Medical Molecular Biology Institute (UMBI), Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
Teck Yew Low
Department of Critical Care Medicine and Hematology, The Third Xiangya Hospital, Central South University; Department of Hematology and Critical Care Medicine, The Third Xiangya Hospital, Central South University, Changsha, China
Ben Lu
Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany
Matthias Mann
School of Life Sciences, Tsinghua University, Tsinghua-Peking Center for Life Sciences, Beijing, China
Anming Meng & Wei Xie
Institute for Systems Biology, Seattle, WA, USA
Robert L. Moritz
Clinical Biomarker Discovery and Validation, Monash University, Clayton, Victoria, Australia
Edouard Nice
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Guang Ning
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai, China
Guang Ning
Shanghai Key Laboratory for Endocrine Tumor, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Guang Ning
Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA
Gilbert S. Omenn
Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, British Columbia, Canada
Christopher M. Overall
Yonsei Frontier Lab, Yonsei University, Seoul, Republic of Korea
Christopher M. Overall
Glycoproteomics Laboratory, Department of Parasitology, University of São Paulo, Sao Paulo, Brazil
Giuseppe Palmisano
Institute of Zoology, Chinese Academy of Sciences, Beijing, China
Yaojin Peng
Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China
Yaojin Peng
University of the Chinese Academy of Sciences, Beijing, China
Yaojin Peng
Institut de Recherche en Santé Environnement et Travail, Univ. Rennes, Inserm, EHESP, Irset, Rennes, France
Charles Pineau
Pilot Laboratory, MOE Frontier Science Centre for Precision Oncology, Centre for Precision Medicine Research and Training, Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macau, China
Terence Chuen Wai Poon
Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia
Anthony W. Purcell
State Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China
Jie Qiao & Liying Yan
ProCan®, Children’s Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, New South Wales, Australia
Roger R. Reddel, Phillip J. Robinson & Qing Zhong
Department of Health Sciences, University Magna Græcia of Catanzaro, Catanzaro, Italy
Paola Roncada
Department of Systems Biology, Harvard Medical School, Boston, MA, USA
Chris Sander
Broad Institute of MIT and Harvard, Cambridge, MA, USA
Chris Sander
State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China
Jiahao Sha & Xuejiang Guo
Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China
Erwei Song & Shicheng Su
Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China
Erwei Song & Shicheng Su
Indian Institute of Technology Bombay, Mumbai, India
Sanjeeva Srivastava
Department of Health Sciences, Faculty of Applied Health Sciences, Brock University, St. Catharines, Ontario, Canada
Siu Kwan Sze
Center for Quantitative Biology, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China
Chao Tang
Department of Chemistry, Southern University of Science and Technology, Shenzhen, China
Ruijun Tian & Chris Soon Heng Tan
State Key Laboratory of Respiratory Health and Multimorbidity, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China
Chen Wang, Yushun Gao, Jie He & Catherine C. L. Wong
Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, China-Japan Friendship Hospital, Beijing, China
Chen Wang
Department of Neurology, Clinical Neuroscience Center, University Hospital Zurich and University of Zurich, Zurich, Switzerland
Tobias Weiss
Technical University of Munich, Freising, Germany
Mathias Wilhelm & Bernhard Kuster
Advanced Genomics Unit, Center for Research and Advanced Studies, Irapuato, Mexico
Robert Winkler
Institute of Translational Medicine, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland
Bernd Wollscheid
Department of Computer Science, National University of Singapore, Singapore, Singapore
Limsoon Wong
Department of Pathology, National University of Singapore, Singapore, Singapore
Limsoon Wong
Guangzhou National Laboratory, Guangzhou, China
Tao Xu, Jing Yang & Nan-Shan Zhong
School of Biomedical Engineering, Guangzhou Medical University, Guangzhou, China
Tao Xu & Tao Xu
The Scripps Research Institute, La Jolla, CA, USA
John Yates
China Science and Technology Exchange Center, Beijing, China
Tao Yun
CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China
Qiwei Zhai
Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, USA
Bing Zhang
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA
Bing Zhang
Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA
Hui Zhang
State Key Laboratory of Medical Proteomics, National Chromatography R. & A. Center, CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China
Lihua Zhang, Yukui Zhang, Hongqiang Qin & Mingliang Ye
School of Mathematical Sciences, Peking University, Beijing, China
Pingwen Zhang
Wuhan University, Wuhan, China
Pingwen Zhang
Institutes of Biomedical Sciences, Fudan University, Shanghai, China
Mingxia Gao, Haojie Lu, Liming Wei, Ying Zhang & Feng Zhou
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
Jun He & Xiaofei Zhang
College of Life Science and Technology, Jinan University, Guangzhou, China
Qing-Yu He & Tong Wang
Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, China
Jinlin Hou
State Key Laboratory of Biotherapy, West China Hospital, and West China School of Basic Sciences & Forensic Medicine, Sichuan University, Chengdu, China
Canhua Huang
Peking University Cancer Hospital & Institute, Beijing, China
Yan Li, Lin Shen & Qimin Zhan
BGI Group, Shenzhen, China
Siqi Liu, Yan Ren & Huanming Yang
Xijing Hospital, Fourth Military Medical University, Xi’an, China
Xiaonan Liu, Ya Liu, Yongzhan Nie & Jianjun Yang
Institute for Protein Research, Osaka University, Osaka, Japan
Mariko Okada
Eastern Hepatobiliary Surgery Hospital, Second Military Medical University (Naval Medical University), Shanghai, China
Guojun Qian & Feng Shen
School of Pharmaceutical Sciences, Tsinghua University, Beijing, China
Yu Rao
School of Medicine, Tsinghua University, Beijing, China
Zihe Rao
Changping Laboratory, Beijing, China
Xianwen Ren, Xiaoliang Sunney Xie & Zemin Zhang
Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai, China
Yan Ren
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
Minjia Tan
School of Science and Engineering, Shenzhen Institute of Aggregate Science and Technology, The Chinese University of Hong Kong, Shenzhen, China
Ben Zhong Tang
Shanghai Center for Systems Biomedicine, Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China
Sheng-Ce Tao
Biomedical Pioneering Innovation Center (BIOPIC), Peking University, Beijing, China
Xiaoliang Sunney Xie & Zemin Zhang
Department of Liver Surgery, Sun Yat-sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China
Li Xu
Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing, China
Yaxiang Yuan
Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing, China
Qingcun Zeng
Peking University International Cancer Institute, Beijing, China
Qimin Zhan
Department of Urology, The Third Medical Center, Chinese PLA General Hospital, Beijing, China
Xu Zhang
State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
Nan-Shan Zhong
F.H. conceived the concept of π-HuB and designed its scientific goals, and contributed ideas for phronesis medicine with L.X., F.H., R.A., M.S.B., X.W.B., X.C.B., D.W.C., C.C., L.C., X.C., H.C., F.C., W.E., J.F., P.F., D.F., G.F.G., W.G., Z.-H.G., K.G., W.W.B.G., D.G., C.G., T.G., A.J.R.H., H.H., T.H., N.G.I., Y.J., C.R.J., L.J., N.L.K., M.L., Y.L., Q.L., C.H.L., F.L., G.-H.L., Y.S.L., Z.L., T.Y.L., B.L., M.M., A.M., R.L.M., E.N., G.N., G.S.O., G.P., Y.P., C.P., T.C.W.P., A.P., J.Q., R.R., P.J.R., P.R., C.S., J.S., E.S., S.S., A.S., S.K.S., C.T., L.T., R.T., J.V.E., J.A.V., C.W., X.W.W., X.X.W., Y.W., T.W., M.W., R.W., B.W., L.W., L.X., W.X., Tao Xu, L.Y., J.Y., X.Y., J.R.Y., Q.W.Z., L.H.Z., L.Q.Z., Y.K.Z., Q.Z. and Y.P.Z. contributed ideas and suggestions for the conception and design of this project. T.G., L.T. and Y.W. contributed coordination of the π-HuB Consortium. J.Y. wrote the first draft of the manuscript, and created the figures with F.H., T.G., Y.L. and L.X. F.H., R.A., M.S.B., F.C., P.F., D.F., Z.-H.G., K.G., W.W.B.G., T.G., H.H., T.H., N.G.I., C.R.J., L.J., M.L., Q.L., F.L., Y.S.L., T.Y.L., R.L.M., G.S.O., T.C.W.P., A.P., R.R., P.J.R., C.S., S.K.S., J.A.V., T.W., R.W., B.W., L.W., J.Y., J.R.Y. and Q.Z. provided important edits to the manuscript. All authors contributed to review and editing of the manuscript. The π-HuB Consortium contributed to the discussion of strategic π-HuB research plans.